Gerador de Marx Bipolar Baseado em Topologia Full-Bridge Aplicado à Eletropermeabilização Biológica

Fernando Imai; Rodolfo L. Weinert; Yales R. de Novaes

doi:10.18618/REP.2021.2.0055

Authors

Fernando Imai Instituto Federal Catarinense, Campus São Bento do Sul – SC, Brasil
Rodolfo L. Weinert Universidade do Estado de Santa Catarina, Joinville – SC, Brasil
Yales R. de Novaes Universidade do Estado de Santa Catarina, Joinville – SC, Brasil

DOI:

https://doi.org/10.18618/REP.2021.2.0055

Keywords:

Eletropermeabilização, Gerador de Marx, Multiplicador de Tensão

Abstract

Este artigo apresenta um circuito Gerador de Marx (GM) bipolar, capaz de gerar pulsos com parâmetros elétricos destinados à eletropermeabilização biológica. Este procedimento consiste em aplicar campos elétricos intensos em tecidos vivos para a criação de poros em suas membranas celulares, e com isso otimizar procedimentos como introdução de medicamentos, transferência genética, fusão molecular e até acelerar a morte de um conjunto celular. É desenvolvido um GM bipolar capaz de obter tensão pulsada de 1200 V a partir de uma entrada em 300 V. O multiplicador de tensão se baseia em um sistema com capacitores conectados ora em paralelo e ora em série. Testes práticos foram realizados com uma amostra vegetal, a fim de analisar o funcionamento do gerador, explorando os múltiplos parâmetros ajustáveis proporcionados pelos circuitos.

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Author Biographies

Fernando Imai, Instituto Federal Catarinense, Campus São Bento do Sul – SC, Brasil

nascido em Curitiba/PR, em 1990, é engenheiro eletricista (2014) pela Universidade Tecnológica Federal do Paraná e mestre (2019) pela Universidade do Estado de Santa Catarina. Desde 2021 é professor do Instituto Federal Catarinense, São Bento do Sul, Brasil.

Rodolfo L. Weinert, Universidade do Estado de Santa Catarina, Joinville – SC, Brasil

nascido em Mafra/SC, em 1992, é engenheiro eletricista (2015), mestre (2017) e doutorando pela Universidade do Estado de Santa Catarina.

Yales R. de Novaes, Universidade do Estado de Santa Catarina, Joinville – SC, Brasil

nascido em Indaial/SC, em 1974, é engenheiro eletricista (1999) pela Universidade Regional de Blumenau, mestre (2000) e doutor (2006) pela Universidade Federal de Santa Catarina. Desde 2010 é professor da Universidade do Estado de Santa Catarina, Joinville, Brasil.

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