Gerador de Marx Bipolar Baseado em Topologia Full-Bridge Aplicado à Eletropermeabilização Biológica
DOI:
https://doi.org/10.18618/REP.2021.2.0055Keywords:
Eletropermeabilização, Gerador de Marx, Multiplicador de TensãoAbstract
Este artigo apresenta um circuito Gerador de Marx (GM) bipolar, capaz de gerar pulsos com parâmetros elétricos destinados à eletropermeabilização biológica. Este procedimento consiste em aplicar campos elétricos intensos em tecidos vivos para a criação de poros em suas membranas celulares, e com isso otimizar procedimentos como introdução de medicamentos, transferência genética, fusão molecular e até acelerar a morte de um conjunto celular. É desenvolvido um GM bipolar capaz de obter tensão pulsada de 1200 V a partir de uma entrada em 300 V. O multiplicador de tensão se baseia em um sistema com capacitores conectados ora em paralelo e ora em série. Testes práticos foram realizados com uma amostra vegetal, a fim de analisar o funcionamento do gerador, explorando os múltiplos parâmetros ajustáveis proporcionados pelos circuitos.
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